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Aggrenox (aspirin, extended-release dipyridamole) is a mix of a salicylate along with a platelet aggregation inhibitor applied to scale back the risk of stroke in Individuals who have experienced blood clots or maybe a "mini-stroke" (also known as a transient ischemic assault or TIA). Aggrenox can be offered in generic kind.
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AGGRENOX is a mix of aspirin and dipyridamole, antiplatelet agents, indicated to cut back the chance of stroke in patients who've experienced transient ischemia in the brain or accomplished ischemic stroke on account of thrombosis (one)
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Dipyridamole has long been documented to increase the plasma stages and cardiovascular effects of adenosine. Adjustment of adenosine dosage may very well be needed. Dipyridamole also increases the cardiovascular effects of regadenoson, an adenosine AA2 -receptor agonist.
Mainly because of the comparable degree of inhibition of adenosine uptake at these plasma concentrations, this food items effect is not regarded clinically applicable.
In ESPS2 people [see Clinical Reports], with creatinine clearances ranging from about fifteen mL/min to >100 mL/min, no improvements had been observed from the pharmacokinetics of dipyridamole or its glucuronide metabolite if info were corrected for variations in age.
Based on facts from a clinical lactation examine in breastfeeding Girls taking very low-dose aspirin, the metabolite salicylic acid is current in human milk in minimal levels (see Data). Dipyridamole is also existing in human milk. There is absolutely no info on the results of AGGRENOX or dipyridamole within the breastfed toddler or on milk output.
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